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Symptoms of vitamin B-12 deficiency include: Fatigue Difficulty concentrating Decreased mood Loss of appetite Poor memory Constipation Higher-risk groups for vitamin B-12 deficiency include people with intestinal disorders such as Crohns or Celiac disease, as well as those who suffer from muscular degeneration, Lou Gehrigs disease or diabetes

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For a loading protocol of 2.5 mg twice per week, reconstituting with 2 mL gives 2.5 mg/mL, so each 2.5 mg dose is 100 units (the full syringe)

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