This update applies to medications like Wegovy (semaglutide) and Zepbound (tirzepatide) when used for weight management
(PubMed) Qin X, Xu M, Zhang Y, et al
Schisphenthin A and schisphenthin C exhibited moderate antiproliferative effects against HepG2 cells
Frequently Asked Questions What is the typical starting dose of semaglutide for weight loss
Other Effects Although not significant in all studies, post-hoc analysis of the placebo-controlled studies in phase III showed that DPP-4 inhibitors slightly lower blood pressure, improve post-prandial and fasting lipemia, reduce inflammatory markers, diminish oxidative stress, improve endothelial function, and reduce platelet aggregation in type 2 diabetes (122)
Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate