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This review included both RCTs and observational studies (N-RCTs, cohort, and case-control) to assess the efficacy of various Vitamin B12 administration routes

Underlying health conditions : In rare cases, complications have been reported with high-dose B12 injections in people with certain heart conditions

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How semaglutide can affect B12 absorption As semaglutide works by slowing gastric emptying and promoting the feeling of satiety (reduced cravings) for weight loss, it may influence the bodys ability to absorb certain nutrients, including vitamin B12

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They help break down Homocysteine, an amino acid that cause toxicity in nerve cells, and they also protect neurons in the brain