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Study 1 This study re-randomized 207 HIV-infected patients with lipodystrophy who completed tesamorelin treatment in the Main Phase to receive either tesamorelin (N=154) or placebo (N=50) for an additional 26-week duration (3:1 randomization ratio)
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Maintenance dosing While definitive maintenance dosing data for retatrutide is still forthcoming, the precedent from other GLP-1 agonists suggests that a reduced maintenance dose may sustain most of the weight loss while minimizing side effects and cost
It is also possible that vagal axons might contact other types of intestinal cells
GLP-1 medications like semaglutide and tirzepatide are possible treatment options that healthcare providers may consider for weight management during menopause
Environ Res 79(1):5168
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