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To mechanistically determine whether 15LO1 pathway activation alters the intracellular redox balance, particularly under T2 conditions, these ex vivo findings were modeled in vitro in primary HAECs

In our experiments, exogenous rapamycin significantly decreased the proportion of SA--Gal-positive cells and p16 expression, whereas autophagy inhibitors 3-MA and Baf-A1 produced opposite effects

Glutathione peroxidase and glutathione S-transferase activity of platelets

Ye et al., 2013), which results in enhanced glutamate release whilst also decreasing its re-uptake (Hu et al., 2000

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Adding glutathione to a base IV incurs $30-$100 additional cost per treatment