Rohayem J, Haffner D, Cremers JF, Huss S, Wistuba J, Weitzel D, Kliesch S, Hohenfellner K (2021) Testicular function in males with infantile nephropathic cystinosis
Shestakova, E., Ilyin, A., Shestakova, M., & Dedov, I
Dalli-Rajhara, Punganur, Mattannur, Mathura, Thakurdwara, Nandivaram-Guduvancheri, Mulbagal, Manjlegaon, Wankaner, Sillod, Nidadavole, Surapura, Rajagangapur, Sheikhpura, Parlakhemundi, Kalimpong, Siruguppa, Arvi, Limbdi, Barpeta, Manglaur, Repalle
As noted by the Alzheimers Drug Discovery Foundation (ADDF), the bulk of research involving epithalamin and epithalon has been conducted in Russia (or formerly, the Soviet Union) and has not been subject to independent confirmation [1]
The answer is not extreme restriction
The natural hormones are highly regulated, and they work in concert together, almost like an orchestra