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The team noted there are some important limitations to keep in mind
The two peptides activate different receptors that converge on growth hormone release, producing 2-3x greater GH pulses than either alone
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It is a triple agonist, targeting GLP-1, GIP, and glucagon receptors simultaneously
The study documented 109 treatment-emergent adverse events, with UC exacerbation and arthralgia being most common
The dual mechanism of action of TZP, targeting both obesity and metabolic dysfunction, makes it a promising therapeutic option for this patient population
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