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[PubMed] [Elsevier] Kanjwal Y, Kosinski D, Grubb BP
Proteomics analysis identified a subgroup of mitochondrial proteins, particularly sensitive to the changes of NADH/NAD + ratio
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57 While the increase of free IGF-2 is associated with the suppression of insulin, IGF-1, and GH serum concentration, 58 the binding of IGF-2 to IGFBPs prevents excessive free IGF-2 in serum to cause hypoglycemia
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The observed differences in free GSH, GSSG, and their respective ratio is likely due to spontaneous oxidation of free GSH in the heparinized plasma rather than a matrix effect of anticoagulant type used during sample collection
