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It is recommended by OARSI that NSAIDs be used at the minimum effective dose and prolonged use should be avoided as much as possible
This hypothesis might have been corroborated by the observation that the levels of the cleaved forms of caspase-3 and PARP, both proteins which may be associated with programmed cell death, seemed to be reduced after introduction of AHK-Cu
Biological changes occur at the cellular level before becoming visible
10.1016/j.freeradbiomed.2007.10.058 44 GeldermanK
Nat Cancer , 5 (7), 10241044
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