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In contrast, nDNA damage was not directly caused by peroxynitrite

These metabolic issues can disrupt the body's energy utilization, lead to fat accumulation, increase metabolic burden, and are detrimental to post-infarction recovery, even raising the risk of complications during the recovery period

The importance of ATM in the cellular response to oxidative stress can be seen by investigating its role in the autosomal recessive disorder ataxia telangiectasia (A-T), after which ATM is named 55

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