Despite adequate oxygenation and circulation, excitatory neurotransmitters and free radicals continue to be released, phosphorus reserves are depleted, inflammatory factors are involved, and brain injury is substantial
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In research settings, the most commonly noted side effects are transient and mild, such as a head rush, flushing, or slight irritation at the injection site
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This suggests that metabolic dysfunction, neuroinflammation, and protein aggregation are not independent processes, but interconnected nodes within the same disease network
Men who tolerate tirzepatide well typically tolerate it better than semaglutide