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The drug met the primary and key secondary endpoints, delivering superior A1C reduction and weight loss at 40 weeks compared to placebo
J Neurosci 28, 465472 (2008)
10.1038/nature26138 84
In one clinical trial , people taking 2 mg of Ozempic per week for type 2 diabetes lost at least 5% and sometimes more than 10% of their body weight after 40 weeks of treatment
Dose considerations during illness Gastrointestinal illness (vomiting, diarrhea) while on semaglutide or tirzepatide creates a compounding effect
A positive control analysis was conducted to validate the genetic instruments for GLP-1R by verifying the association of genetic instruments from eQTLs with type 2 diabetes, given that GLP-1R agonists are FDA-approved for blood glucose and weight control
