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doi: Mielgo-Ayuso, J., Pietrantonio, L., Viribay, A., Calleja-Gonzlez, J., Gonzlez-Bernal, J

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Likewise, any published information relative to the dosing and administration of reference materials is made available strictly for reference and shall not be construed to encourage the self-administration or any human use of said reference materials

[14] successfully isolated exendin-4 from the venom of the Gila monster (Heloderma suspectum), a lizard known for its infrequent but large meals weighing up to as much as one third of its body masssuggesting the presence of adaptive metabolic mechanisms in the species [14,15]

Long-term hyperglucagonaemia induces early metabolic and renal phenotypes of type 2 diabetes in mice

Thus treatment of mice with the GLP-1 agonist exendin 4 reduced beta-cell apoptosis induced by streptozotocin (while GLP-1 receptor knockout mice were abnormally susceptible to streptozotocin-induced beta-cell apoptosis) (169)