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This is not due to a direct chemical interaction, but rather an additive effect on the digestive system
It can cause sudden shortness of breath, chest pain, rapid heart rate, lightheadedness, or coughing up blood
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Therefore, in addition to their effects on insulin secretion, GLP-1 and GIP also have other metabolic effects, such as reducing glucagon secretion from the pancreas, slowing down gastric emptying and promoting satiety
The effectiveness and safety of this option can vary depending on the compounding pharmacy's practices
The SURPASS-1 to -5 clinical trials assessed the efficacy of once weekly tirzepatide (5, 10 or 15 mg) versus placebo and active comparators
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