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Patients with active, moderate-to-severe GO, are generally treated with high doses intravenous glucocorticoids (ivGCs) and/or orbital radiotherapy

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When B12 injections are obtained outside regulated healthcare settingssuch as from wellness clinics or online providersadditional risks emerge

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However, tumor cells often compete with normal cells, including immune cells, for nutrients in the tumor microenvironment (Buck et al., L-Arginine is a multifunctional amino acid