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[67] For a time, bovine liver SOD even had regulatory approval in several European countries for such use

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Rundle AG, Orjuela M, Mooney L, Tang D, Kim M, Calcagnotto A, Richie JP, Perera F

No trial reported on clinical signs and symptoms of vitamin B 12 deficiency, health-related quality of life, or acceptability of the treatment scheme Orally taken vitamin B 12 showed lower treatment-associated costs than intramuscular vitamin B 12 in one trial

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For those who are comfortable incorporating oral supplements, this can be a relatively straightforward enhancement to their clearance of melasma