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Regular physical activity is particularly crucial for weight maintenance, with guidelines recommending at least 200 to 300 minutes of moderate-intensity exercise weekly plus resistance training 2-3 days per week for individuals maintaining significant weight losssubstantially more than the 150 minutes recommended for general health per the Physical Activity Guidelines for Americans

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According to Table 3 , a characteristic pro-inflammatory state can be observed in SZ patients, manifested by persistently elevated levels of pro-inflammatory cytokines such as IL-6, IL-1, and TNF- in both peripheral blood and CSF, accompanied by a relative deficiency of anti-inflammatory cytokines like IL-10 and TGF-