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Retatrutide has not received marketing authorisation from the MHRA, EMA, or any regulatory body, and is not available via NHS prescribing

In a 2024 joint court filing, the two companies said that the safety profile of GLP-1 RAs has been well-established in hundreds of clinical trials, large-scale observational studies, and nearly two decades of real-world use

The combined BP-lowering effect could be clinically relevant in patients who are also on antihypertensive medications

They can order tests to assess thyroid function or identify other factors that may make weight loss more difficult

In: Choi I-Y, Gruetter R, ediotr

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