This iron-sequestering capability is particularly important because excess free iron directly enters cells, concentrates in mitochondria, disrupts oxidative phosphorylation, catalyzes lipid peroxidation, and ultimately leads to cell death
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Whats remarkable is how a simple daily ritual enjoyed by billions worldwide is revealing sophisticated anti-cancer mechanisms that could complement conventional treatments (Zhang et al
The link between this principle and autoimmune diseases was then shown in the 1980s, when Imbach and colleagues found that injection of a large pool of exogenous IgG (IVIg) alleviated idiopathic thrombocytopenia (ITP) [94,95,96]