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This limitation is particularly evident in 3D tumor spheroid cultures, where the abundant ECM components form a more physiologically relevant barrier than traditional 2D monolayers, leading to reduced drug penetration and attenuated therapeutic response [135]

[PMID: 11459660] PubMed record related to this compound for laboratory literature review

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ALCAR can provide an acetyl moiety that can be oxidized for energy, used as a precursor for acetylcholine, or incorporated into glutamate, glutamine and GABA, or into lipids for myelination and cell growth

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