As noted, a significant subset of ED patients (~30% or more) do not respond fully to PDE5is
Zepbound is approved to treat obesity and Mounjaro is approved for diabetes
PlexusDx's Precision Peptide Genetic Test ($298) analyzes variants in GIPR and FTO, and MC4R genes, among 49 peptides across 14 pathways
Cardiovascular Diabetology Endocrinology Reports , 2026
Fat burning injections: This treatment injects a variety of chemicals into the patients body
However, in partial responders or those unable to escalate dose, future strategies may involve agents such as peripherally acting cannabinoid type 1 receptor antagonists, FGF21 analogs, amylin mimetics, or emerging triple agonists like retatrutide, which target GLP-1, GIP, and glucagon receptors simultaneously