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AMINO-1MQ (5-Amino-1MQ) NNMT Inhibitor Research Compound AMINO-1MQ (5-amino-1-methylquinolinium) is a small-molecule, membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT) , an enzyme involved in cellular methylation and NAD+ metabolism

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They found that sedentary mice treated with 5-amino-1MQ and mice that underwent vigorous exercise had significantly lower levels of muscle cell fats, suggesting improved muscle quality

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PMC8337113