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The primary preclinical evidence comes from mouse studies showing reduced body weight and adipose mass in diet-induced obese mice (2018), improved grip strength in aged mice (2024), and beneficial microbiome changes when combined with caloric restriction (2022)
Distinct nasal airway bacterial microbiotas differentially relate to exacerbation in pediatric patients with asthma
Tolar J, Orchard PJ, Bjoraker KJ, Ziegler RS, Shapiro EG, Charnas L
The NHS does not endorse or recommend unregulated peptide pills for weight loss
Effect of multispecies probiotic supplements on metabolic profiles, hs-CRP, and oxidative stress in patients with type 2 diabetes
Similarly to type I IFNs, IFN- activates JAK/STAT signaling but binds to the heterodimeric receptors IL-10RB and IFNLR1
