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For instance, in a model of APAP-induced liver injury, the protective antioxidant and anti-inflammatory effects of the bioflavonoid naringin are highly dependent on the upregulation of both CHAC2 and NRF2 (Zhai et al., 2022)

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The Hepatitis C virus (HCV) relies on the hosts production of phosphatidylcholine for its own replication, a mechanism driven by the viral NS3/4A protease