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Dosage level directly correlates with side effect duration and intensity

10.7150/thno.40735 32 LiY.ZhaoZ.LuoJ.JiangY.LiL.ChenY.et al (2021)

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This metabolite was discovered to mitigate ectopic lipid deposition in renal tubular cells, indicating the presence of a gut microbiota5-OPkidney axis (potentially mediated by Clostridium5-OPELD), which may serve as a novel intervention target (Steven et al., 2017

However, GLP-1R siRNA weakened the effect of liraglutide (Supplementary Figure S3cf)

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