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It is administered by intramuscular (IM) injection
But the weight loss process itself can trigger inflammatory responses, particularly in joints and connective tissue as the body adapts to carrying less weight
My own practice has seen countless patients who have tried both medications unequivocally prefer Zepbound for its combination of efficacy and tolerability
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The 6-Week Check: Catching Early Signals Six weeks is long enough for CJC-1295 DAC to reach pharmacodynamic steady state but short enough to catch problems before they calcify into clinical events
There was less certainty regarding the relative effects of the drugs to each other, particularly for outcomes beyond weight loss (e.g., cardiovascular outcomes), for which reason the institute judged the comparison between tirzepatide and semaglutide as promising but inconclusive (P/I)
In the case of tirzepatide (Mounjaro /Zepbound ), the prescribing information specifically warns that treatment should only be restarted if the benefits clearly outweigh the risks and your provider agrees its safe to do so
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