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If you take other diabetes medications, particularly insulin or sulfonylureas, there is an increased risk of hypoglycaemia

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Dipeptidyl-Peptidase IV (CD26)-Role in the Inactivation of Regulatory Peptides

Thus, IcoSema and separate administration of a component was considered equivalent with respect to a given endpoint if the 90% CI of their estimated mean treatment ratio was fully contained within the range of 80125%