Accepted: Apr 23, 2025 DOI: Download citation
I figured at that point I had nothing to lose except maybe a bit more insecurity
For example, if you added 4 mL instead of 2 mL, each unit on your syringe will contain half the dose you originally planned for
Bring your symptom diary if you have kept one, and be ready to describe: When symptoms began in relation to starting or increasing the dose How often you are experiencing bowel changes and what they look like Whether symptoms are improving, worsening, or staying the same What you have already tried to manage them and whether it helped How much the symptoms are affecting your daily life and wellbeing Your prescriber may consider adjusting your dose-escalation schedule, recommending specific dietary changes, or referring you to a gastroenterologist if symptoms are complex or persistent
& Jowsey, I
Clinical trials for high-dose oral semaglutide (such as the OASIS trial) have shown that a daily 25mg or 50mg pill can produce weight loss results reaching roughly 14% on average, putting it on par with weekly injections
