CrossRef Development of a Lipidomics-Based Cell Screening Platform for Indirect Antioxidants Targeting Oxidized Lipid Droplet Formation and Mitochondrial Membrane Abnormality Yuzu Shibata, Toshihiro Sakurai, Akiko Sakurai, Misuzu Sato, Shu-Ping Hui Nutrients .2026
Most side effects are mild to moderate, occur during dose escalation, and improve over time
No lethal dose has been identified
According to one study, participants taking prednisone reported increased appetite resulting in weight gain
An imbalance between free radical production and the bodys antioxidant defenses leads to oxidative stress, which is implicated in the pathogenesis of numerous diseases (Table 2) [8]
Other medications with some evidence but not FDA approval include certain SSRIs and topiramate