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PLoS One 20 (9), e0321839

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One legitimate concern the authors raise is discontinuation

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When the body is trapped in the vicious cycle of oxidative stress and mitochondrial degradation, targeted intervention is required to break the loop

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Consequently, targeting glutathione biosynthesis has emerged as a promising therapeutic approach in malignancies such as breast cancer and diffuse large B-cell lymphoma, where disrupting this redox-sensitive signaling network can suppress tumor growth and metastatic potential [50]

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