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Efficacy and safety of a fixed-ratio combination of insulin degludec and liraglutide (IDegLira) compared with its components given alone: results of a phase 3, open-label, randomised, 26-week, treat-to-target trial in insulin-naive patients with type 2 diabetes
Another milestone in the evolution of GLP-1-based diabetes therapies
Cavalieri EL, Stack DE, Devanesan PD, Todorovic R, Dwivedy I, Higginbotham S, Johansson SL, Patil KD, Gross ML, Gooden JK, et al
We titrate slowly to improve comfort and sustainability
The American Diabetes Association similarly recommends at least 150 minutes of moderate-intensity exercise weekly, spread over at least 3 days, with no more than 2 consecutive days without activity
If lipohypertrophy develops, it may take several months of avoiding that site for the tissue to recover
