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All participants who had more than one episode of DKA were from the SGLT2i group
This partly explains why side effects including injection site reactions often diminish over time rather than worsen
In contrast, reproductive outcomessuch as hormonal profiles, ovulation, and pregnancyshow greater cross-study fluctuation
Research connects substantial preconception maternal weight loss to reduced rates of miscarriage and fewer obstetric complications including gestational diabetes and hypertensive disorders
None of these is a proven, approved therapy in the United States
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