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Continue reading References The rationale, design and baseline data of FLOW, a kidney outcomes trial with once-weekly semaglutide in people with type 2 diabetes and chronic kidney disease Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial Once-Weekly Semaglutide in Adults with Overweight or Obesity Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes Ozempic Prescribing Information - Injection Ozempic Tablets Prescribing Information FDA approves Ozempic (semaglutide) as the only GLP-1 RA to reduce the risk of worsening kidney disease and cardiovascular death in adults with type 2 diabetes and chronic kidney disease More about Ozempic (semaglutide) Check interactions Compare alternatives Pricing & coupons Reviews (1,698) Drug images Latest FDA alerts (6) Side effects Dosage information Patient tips During pregnancy Support group FDA approval history Drug class: GLP-1 Drugs Breastfeeding En espaol Patient resources Other brands Professional resources Other brands Related treatment guides Further information Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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Impaired activity of methionine synthase results in elevated blood concentrations of homocysteine, while impaired activity of L-methylmalonyl-CoA mutase results in increased concentrations of a metabolite of methylmalonyl-CoA called methylmalonic acid (MMA) in blood and urine