In transmethylation, the conversion of homocysteine to methionine is catalyzed by the enzyme methionine synthase, a vitamin B12-dependent zinc protein (Figure 3)
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However, these methods have also a disadvantage associated with a difficulty of application thereof to industrial-scale production due to a low concentration of reactants and a prolonged reaction time of 2 to 3 days
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It plays a crucial role in regulating blood sugar levels by stimulating insulin release, slowing down gastric emptying, and reducing glucagon production, contributing to overall glucose control
Studies have found that people who experience migraines are more likely to have low B12 levels than people with no migraine history