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Modulation of expression of rat mitochondrial 2-oxoglutarate carrier in NRK-52E cells alters mitochondrial transport and accumulation of glutathione and susceptibility to chemically induced apoptosis

Using CRISPR-Cas9 in human and mouse cells, genome-wide, targeted loss-of-function pooled screens have been studied that has provided information about the inactivated genomic loci and strategies that modulate transcriptional activities (Shalem et al., 2015)

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As stated above, GLP-1 receptor agonists work by slowing gastric emptying and increasing the feeling of satiety, which can be related to the weight loss seen with this agent

The coming decade of cell death research: five riddles

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