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Semaglutide's delay of gastric emptying could potentially alter the absorption profile of oral medications, including modified-release stimulant formulations
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For Hashimoto's patients, this discontinuation requires careful planning because: Thyroid hormone requirements increase significantly during pregnancy (typically 25-50% higher) Weight regain after GLP-1 discontinuation will change levothyroxine requirements again Optimal thyroid function before conception is critical for fetal brain development If you discover you are pregnant while on a GLP-1 medication , stop the medication immediately and contact your healthcare provider for urgent thyroid function testing and levothyroxine dose adjustment
SMARCA4, SMARCB1, and PBRM1 are subunits of cBAF/PBAF/ncBAF, cBAF/PBAF, and PBAF, respectively
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Cymbal, Michael et al
