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Western blot Proteins were extracted from cells and tissues using RIPA lysate containing protease inhibitors and phosphatase inhibitors
Different studies showed that higher levels of pro-inflammatory cytokines in the CSF and plasma support the interaction between the brain and the immune system with the development of neuroinflammation and degeneration of dopaminergic neurons in PD (Jiang and Dickson 2018
Nanoparticle formulations of the Parkinsons drug, selegiline, resulted in 12-20 fold increases in brain concentrations in laboratory animals compared to delivering the drug orally
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