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What do patients need to know about switching medications
If you're using semaglutide, tirzepatide, Ozempic, Wegovy, Mounjaro, Zepbound, or another medically supervised weight loss tool, your macros should reflect your actual situation
Increase GLP-1 with food
In particular, signals from the gut can activate specialized neurons of the arcuate nucleus (ARC) that regulate energy and glucose homeostasis, including agouti-related peptide/neuropeptide Y orexigenic neurons and pro-opiomelanocortin/cocaine and amphetamine-regulated transcript anorexigenic neurons 22,33,34,35
Key Takeaways Tirzepatide slows down digestion without harming enzymes
Lipid metabolism The effects of NRF2 on lipid metabolism are less well characterized
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