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This difference in CV benefit observed in the trials has important clinical implications regarding how to use the two classes of agents and how to identify suitable patients to obtain the best benefit from each class during routine diabetes care, possibly leading to a treatment plan tailored to an individual patients CV risk and clinical condition

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For patients who respond to these medications, we would anticipate that [they] would respond with weight loss within the first month, she says

It is not approved for human consumption or therapeutic use in the UK

For CNS studies, GLP-1R knockout models or GLP-1R-negative cell lines as receptor-negative controls are essential

Mean changes in blood pressure were comparable between the two treatment groups