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Since kidney function is reduced during AKI, activation of the urea cycle and subsequent urea generation together lead to a substantial rise in BUN 14,35

Sasaninia K, Kelley M, Abnousian A, Badaoui A, Alexander L, Sheren N, Owens J, Rajurkar S, Razo-Botello B, Chorbajian A, Yoon S, Dhama S, Avitia E, Ochoa C, Yutani R, Venketaraman V

Kidney Problems: Dehydration from side effects like nausea, vomiting, or diarrhea can strain the kidneys

It is one of the most common causes of cloudy solution and reduced effectiveness

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Venter H, Genade S, Mouton R, Huisamen B, Harper IS, Lochner A