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Demonstrating a direct, weight-independent hepatic effectparticularly mediated through LSECsadds an entirely new layer of biological plausibility and therapeutic relevance
Individual results may vary based on age, baseline tissue health, and adherence to the prescribed protocol
Sugar-free gum or xylitol-containing lozenges may help stimulate saliva production, while patients with severe xerostomia may require a prescription for pilocarpine
Someone carrying extra weight who still runs half marathons, with normal blood sugar, normal labs, and good energy, has what the commission calls preclinical obesity: a state worth watching, with elevated future risk, but not necessarily one that demands aggressive treatment today
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