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When co-treated with Fer1, the PI uptake was effectively suppressed in the RSL3-treated 3D PTC spheroids, further reinforcing our previous findings of cytoprotective effects and ferroptosis pathway abrogation by Fer1 in RSL3-treated PTC cells in 2D
10.1089/ars.2006.8.813 Antioxid Redox Signal
Cellular: protein synthesis and tissue recovery mechanisms
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Experimental inhibition of DRP1 using pharmacological agents such as Mdivi-1 mitigates mitochondrial fragmentation and reduces viral replication, underscoring the functional significance of mitochondrial dynamics during infection (Xu et al., 2025)
In these severe cases, surgery can help prevent permanent nerve and muscle damage
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