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Pigment epithelium-derived factor (PEDF), the overexpression of which upregulated GPX4 and FTH1 that proved to suppress LPO and ferroptosis induced by NaIO 3 , was recently viewed as an upstream regulatory molecule of RPE ferroptosis (86)

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In 2-weeks-old hairy root cultures, the relative transcript amount of NtGST was rather oscillating, while, in 3-weeks-old hairy root cultures, the expression pattern was similar to that in seedlings