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Taking your shot with food and staying hydrated can help minimize this
Use of tirzepatide in the pivotal phase 3 SURMOUNT-3 and SURMOUNT-4 clinical trials was associated with mean weight loss of 26.6% among participants with Combined, the latest findings in the companys clinical trial program evaluating the novel dual incretin mimetic for weight management showed the highest level of weight loss observed in the SURMOUNT program to date," the company stated
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The absence of a significant eGFR change in our cohort likely reflects lower baseline kidney risk and the shorter observation period: baseline eGFR was ~ 76 ml/min/1.73 m 2 versus ~ 47 ml/min/1.73 m 2 in FLOW, and our follow-up was 1 or 2 years versus a median 3.4 years in FLOW, which may be insufficient to detect meaningful eGFR differences in earlier-stage T2D
Anything noticed inside 48 hours is more plausibly the mild inflammatory malaise reported anecdotally after doses than a therapeutic effect
