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however, in most cases, osteoporosis is predominantly driven by excessive osteoclast activity (16).Because the resorption phase of bone remodeling is shorter than the formation phase, such that even modest increases in resorption can lead to bone loss (17, 18), indicating that any increase in bone resorption will likely lead to loss of bone mass (18)

doi: 10.1186/s12967-021-02745-1 52 SuYLucasRFultonDJRVerinAD

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