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UK B12 treatment for B12 deficiency without neuro symptoms is 6 loading jabs over 2 weeks followed by a jab every 3 months for B12 deficiency with neuro symptoms present, it is a B12 loading jab every other day for as long as symptoms continue to get better (could mean loading jabs for weeks even months) then a jab every 2 months UK b12 documents BMJ B12 article bmj.com/content/349/bmj.g5226 BSH Cobalamin and Folate Guidelines b-s-h.org.uk/guidelines/gui

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For extended storage, freezing the powder maintains potency for years

It is one of the two bioactive forms of B12 that the body can use directly without conversion

gastric parietal cells, which make intrinsic factor (a stomach protein that enables the body to absorb B12), become less functional with age