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Pais R, Gribble FM, Reimann F

GLP-1 drugs contributed to the uptick in activity

This reduces oxidative DNA damage within melanocytes, diminishing the triggers that upregulate melanin production in the first place

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Compounded tirzepatide requires caution because compounded drugs are not FDA-approved, and broad shortage-based compounding became restricted after FDA determined the tirzepatide shortage was resolved

Many of these medicines are often quite effective at reducing symptoms and preventing severe flare-ups