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We incorporated our genetic findings into broader models that combine demographic, clinical and genetic features to predict efficacy and side effects, and demonstrated the ability of this model to stratify patients by weight loss in a held out electronic health record (EHR) dataset

Charlie Seltzer, M.D., an obesity specialist based in Philadelphia

When administered intravenously, it bypasses digestion and enters the bloodstream directly

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Rare but serious risks include pancreatitis, gallbladder disease, and thyroid tumors (seen in rodent studies

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