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found that GLP-1-based therapies, including exenatide or sitagliptin, could significantly lower BP in the same manner as insulin therapy (121), thus suggesting that the hypotensive effects of insulin may be associated with GLP-1 (122)

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This is thought to result from direct hormonal effects as well as the secondary benefits of weight loss induced by the medications

Ann Surg 200:405-412, 1984

Ozempic Ozempic is an FDA-approved semaglutide medication to manage type 2 diabetes