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Semaglutide for management of obesity in adolescents: Efficacy, safety, and considerations for clinical practice

GLP-1 agonists and changes in body mass and composition in adults with overweight or obesity with or without type 2 diabetes mellitus: a systematic review and meta-analysis

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For injectable protocols, maintaining consistent spacing between administrations optimizes blood levels

Proven alternatives deliver comparable results with established safety: tirzepatide monotherapy produces 15-22% weight loss with FDA approval and extensive clinical data, while CagriSema (cagrilintide + semaglutide) delivers 15-25% weight loss with Phase 3 trial validation and clearer path to medical acceptance

2 AnathyV.RobersonE